Thursday, February 11, 2016

Folic Acid Consumption in Pregnancy May Raise Gestational Diabetes Risk – Endocrinology Advisor

Taking folic acid during the first trimester of pregnancy is linked to an increased risk for gestational diabetes.
Taking folic acid throughout the initial trimester of pregnancy is associateded with an improved danger when it come to gestational diabetes.

(HealthDay News) — Folic acid intake in the initial trimester is connected along with improved danger when it come to gestational diabetes mellitus, based on study provided in Diabetes Care.

Beibei Zhu, from the Anhui Health care University in Hefei, China, and colleagues utilized data from the possible China-Anhui Childbirth Cohort Study to examine the correlation in between folic acid supplement intake and the danger when it come to gestational diabetes.

The researchers identified gestational diabetes in 12.8% of the 1938 ladies that possessed either utilized folic acid supplements or never ever utilized any sort of supplement supplements. The danger when it come to gestational diabetes was improved in organization along with everyday folic acid supplement intake in the initial trimester (adjusted probabilities ratio [OR]=2.25). 

The danger when it come to gestational diabetes was considerably greater when it come to ladies along with a prepregnancy physique mass index (BMI) of 25 kg/m² or higher and taking folic acid supplements everyday in the initial trimester vs ladies along with a prepregnancy BMI of much less compared to 25 kg/m² and no longer taking folic acid supplements (OR=5.63). 

Women utilizing folic acid prior to pregnancy alone or in the 2nd trimester alone possessed absolutely no improved danger when it come to gestational diabetes.

“Our study, when it come to the initial time, indicates that everyday folic acid supplement intake in very early pregnancy enhances the danger of gestational diabetes mellitus, and more bigger cohort studies are warranted to examine this side effect,” the researchers wrote.

Reference

  1. Zhu B, Ge X, Huang K, et al. Folic Acid Supplements Consumption in very early Pregnancy enhances danger of Gestational Diabetes Mellitus: Proof From a possible Cohort Study. Diabetes Care. 2016. doi:10.2337/dc15-2389.